Apparently eight fatal instances of Clostridium sordellii infection in women who had just given birth have also been reported in medical literature and the CDC says last month it has discovered reviews of two fatal cases of the same illness in ladies who had miscarriages in their second trimester. Some specialists wonder if RU-486 might suppress the immune system, which would increase susceptibility to bacteria already present in the vaginal canal. They state pregnancy suppresses the disease fighting capability, and the dilation of the cervix, whether due to abortion, childbirth or miscarriage, which may let bacteria penetrate much deeper into the body also. Various species of Clostridium bacteria are found in roughly one in 1 naturally,000 women. Mifepristone works by blocking a hormone required to sustain a pregnancy and when implemented two days afterwards by another medication, misoprostol, induces contractions, and the pregnancy is terminated..The increase is mainly because of a comparative increase in product sales of Cetrotide to particular customers in the initial quarter of 2010. This boost was partly offset by lower amortization of upfront permit fee payments this year 2010 related to our contract with sanofi-aventis U.S. LLC , which was entered into in March 2009, regarding the our now discontinued advancement program including cetrorelix for the treating Benign Prostatic Hyperplasia , and subsequently terminated. Research and development costs, net of taxes credits and grants, were $5.7 million for the three-month period ended March 31, 2010, compared to $11.4 million for the same period in ’09 2009. The comparative reduction in net R&D costs is nearly entirely attributable to the winding down and termination of development activities linked to cetrorelix in BPH, regardless of the presence in the first one fourth of 2010 of residual expenditures associated with certain remaining contractual obligations.