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The analysis may also offer brand-new insights into bone loss connected with osteoarthritis and osteoporosis.. Adseverin protein plays essential role in bone loss connected with osteoinflammatory disease Adseverin, a protein within the body, has been defined as the key driver behind the bone loss linked to the world's most common inflammatory disease: gum disease, or periodontitis. The results, released this month in top biology journal FASEB by researchers at the University of Toronto's Faculty of Dentistry, paves the real method for new preventive treatment versions because of this prevalent disease.