Outcomes according to mutation status are provided in Fig. 3 in the Supplementary Appendix. Adverse-Event and Safety Profile Table 2Table 2Adverse Occasions. Lists the most typical adverse events.7 percent vs. 61.0 percent), a lower rate of adverse occasions resulting in discontinuation of the drug , and a lower rate of dose modification because of toxic results . Adverse events leading to death occurred in 3.8 percent of the sufferers treated with gefitinib and in 2.3 percent and 15.6 percent of sufferers in the two groups, respectively; and severe adverse events leading to hospitalization occurred in 13.8 percent and 13.1 percent of patients in the two groups, respectively.Second, by 2015, this program aimed to reduce the rate of contamination in humans to significantly less than 1 percent.4,6,20 To reach these targets, the Ministry of Wellness recognized an urgent have to create a new schistosomiasis control strategy for China. Based on studies identifying cattle as the principal source of S. Japonicum infection for the oncomelania snails and the limited life time of contaminated snails,10,21 we developed a comprehensive control strategy aimed at reducing the roles of cattle and human beings as sources of an infection for snails.21 In this survey, we describe the execution of this strategy in an endemic area throughout a 30-month period from 2005 through 2007. We provide an evaluation of the effectiveness of the strategy and discuss the adoption of this approach as a national strategy to control transmission of S.